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Pineal Tetrapeptide — Telomere & Longevity Research
NA-Epitalon

Pineal Tetrapeptide — Telomere & Longevity Research

Buy NA-Epitalon

Not For Human Use, Lab Use Only.

Synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the natural pineal peptide epithalamin. 30+ years of research by Khavinson et al. — telomerase activation, anti-aging, and melatonin restoration.

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≥98% Purity

HPLC Verified

Research Grade

Lyophilized

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Specifications

CAS Number307297-39-8
SequenceAla-Glu-Asp-Gly
Molecular Weight390.35 g/mol
Molecular FormulaC₁₄H₂₂N₄O₁₀
Storage−20°C (lyophilized, 24 months) · 4°C in solution
Purity≥98% HPLC verified

NA-Epitalon — Molecular Activity & Targets

Pathway 01

Telomerase Activation

Khavinson's landmark research showed Epithalon stimulates telomerase (hTERT) expression in human fetal fibroblasts — allowing cells to extend their telomeres and replicate beyond the normal Hayflick limit without malignant transformation. This is the primary proposed mechanism for its life-extension effects.

Pathway 02

Pineal Gland Restoration & Melatonin

Epithalon stimulates melatonin synthesis in the pineal gland. Pineal function and melatonin production decline significantly with age. Restoration of melatonin pulsatility improves circadian rhythm regulation, sleep architecture, and immune function.

Pathway 03

Antioxidant & Anti-Inflammatory Activity

Epithalon exhibits free radical scavenging activity and upregulates antioxidant enzymes including SOD and catalase. Reduces oxidative stress — a primary driver of cellular aging — at both the nuclear and mitochondrial level.

NA-Epitalon — Catalog Disclaimer

This page summarizes identity, purity, and handling context for catalog navigation. It is not medical advice, a drug label, or a summary of clinical outcomes for any use. Materials are sold for legitimate laboratory research only; verify requirements with your institution and the supplier.

Buying NA-Epitalon: Reconstitution Reference

Illustrative ranges from published laboratory work—reference only, not a protocol for use.

  1. 01

    Subcutaneous Injection

    5–10 mg/day / Once daily for 10–20 day course, 2–3x/year

    Most studied protocol follows a 'course' model rather than continuous dosing.

NA-Epitalon — Vial-Specific Reconstitution

50mg vial + 2mL BAC water = 25mg/mL. For a 5mg daily dose draw 0.2mL. For 10mL BAC water → 5mg/mL (1mL per dose — Khavinson-protocol concentration).

Epitalon is a 4-AA tetrapeptide — one of the fastest-dissolving peptides. Exceptionally stable in solution: 4–6 weeks at 2–8°C without meaningful degradation.

NA-Epitalon — Stacks Well With

GHK-Cu

Epithalon addresses cellular aging at the telomere level; GHK-Cu addresses tissue aging at the collagen and gene-expression level. Together they form a multi-mechanism longevity research stack.

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