Nicotinamide Adenine Dinucleotide — Cellular Energy Cofactor
Buy NAD+
Not For Human Use, Lab Use Only.
Essential coenzyme in all living cells — required for cellular energy production, DNA repair, and sirtuin-mediated longevity pathways. Declines ~50% between age 40 and 60.
≥98% Purity
HPLC Verified
Research Grade
Lyophilized
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Specifications
NAD+ — Receptor Pathways
Cellular Energy Production (Krebs Cycle / ETC)
NAD+ is an essential electron carrier in the mitochondrial electron transport chain, accepting electrons from the Krebs cycle and enabling ATP synthesis. Without sufficient NAD+, mitochondrial efficiency drops and cellular energy production declines — a hallmark of biological aging.
Sirtuin Activation (SIRT1–7)
Sirtuins are NAD+-dependent deacylases that regulate gene expression, DNA repair, and metabolic homeostasis. SIRT1 and SIRT3 have been most studied for longevity and metabolic effects. NAD+ availability is rate-limiting for sirtuin activity — raising NAD+ levels directly increases sirtuin function.
PARP-Mediated DNA Repair
PARP (poly ADP-ribose polymerase) enzymes consume NAD+ to repair DNA strand breaks. As DNA damage accumulates with age, PARP activity increases and NAD+ is depleted — creating a vicious cycle. Restoring NAD+ supports PARP's ability to maintain genomic integrity.
NAD+ — Research-Use Notice
This page summarizes identity, purity, and handling context for catalog navigation. It is not medical advice, a drug label, or a summary of clinical outcomes for any use. Materials are sold for legitimate laboratory research only; verify requirements with your institution and the supplier.
Buying NAD+: Vial Math & Handling
Illustrative ranges from published laboratory work—reference only, not a protocol for use.
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IV / Subcutaneous Injection
250–500 mg / 2–3x weekly or daily
Injectable NAD+ provides direct systemic availability. IV administration produces rapid effects (often within 1–2 hours). Subcutaneous administration is slower-onset but comparable total bioavailability.
NAD+ — Reconstitution Notes
500mg vial + 5mL BAC water = 100mg/mL. For a 250mg dose draw 2.5mL; for 100mg draw 1mL. NAD+ dissolves readily with minimal swirling.
Unlike peptides, NAD+ is less stable post-reconstitution — use within 24–48 hours of mixing. For longer protocols, reconstitute smaller volumes on demand rather than the full vial.
NAD+ — Pair This With
Epithalon
Epithalon targets telomere biology; NAD+ supports the cellular energy and sirtuin-mediated maintenance processes that depend on telomere integrity. Together they address two distinct but related hallmarks of cellular aging.
GHK-Cu
NAD+ restores cellular energy and DNA repair; GHK-Cu activates collagen synthesis and tissue repair genes. Complementary longevity and regeneration mechanisms.
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NAD+
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