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Longevity ResearchApollo Peptide Sciences

Anti-Aging Peptides

Peptides investigated for their roles in cellular longevity, telomere maintenance, skin regeneration, and age-related decline.

4,000+
Genes activated by GHK-Cu
Broad Institute 2012
-60%
GHK-Cu plasma decline by 60
vs age-20 levels
50+ yrs
Epithalon telomere research
Dr. Khavinson, St. Petersburg
≥98%
Purity guarantee
Apollo Peptide Sciences

Anti-Aging Peptides: Research Overview

Aging research has identified several peptide compounds that interact with fundamental cellular processes including telomere maintenance, DNA repair, mitochondrial function, and extracellular matrix remodeling.

Key Peptides

Epithalon (Epitalon) Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the natural peptide epithalamin produced by the pineal gland. Research by Dr. Vladimir Khavinson demonstrated that Epithalon activates telomerase, the enzyme responsible for maintaining telomere length. Telomere shortening is a hallmark of cellular aging, and telomerase activation has been associated with extended cellular lifespan in vitro studies.

GHK-Cu (Copper Peptide) GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. First identified in human plasma by Dr. Loren Pickart, GHK-Cu levels decline significantly with age (from ~200 ng/mL at age 20 to ~80 ng/mL by age 60). Research has demonstrated its role in:

  • Stimulating collagen and glycosaminoglycan synthesis
  • Promoting angiogenesis and nerve outgrowth
  • Possessing anti-inflammatory and antioxidant properties
  • Activating wound healing and tissue remodeling genes
NAD+ (Nicotinamide Adenine Dinucleotide) NAD+ is a coenzyme essential for cellular metabolism and energy production. It serves as a substrate for sirtuins (SIRT1-7) and PARPs, which are involved in DNA repair, gene expression, and cellular stress responses. NAD+ levels decline with age, and research into NAD+ supplementation focuses on restoring cellular function and metabolic health.

SNAP-8 SNAP-8 (Acetyl Glutamyl Heptapeptide-3) is a synthetic octapeptide researched for its effects on SNARE complex modulation. By interfering with the protein complex required for neurotransmitter release, it has been studied as a topical alternative to botulinum toxin for reducing expression lines.

Research Applications

  • Telomere biology and cellular senescence
  • Skin aging and collagen synthesis
  • Mitochondrial function and NAD+ metabolism
  • Wound healing and tissue remodeling
  • Neuromuscular junction studies
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Research-Grade Anti-Aging Peptides

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Frequently Asked Questions

How does Epithalon affect telomeres?

Epithalon has been shown in research to activate telomerase, the enzyme that adds telomeric repeats to chromosome ends. By maintaining telomere length, it may help extend cellular replicative capacity.

What is GHK-Cu used for in research?

GHK-Cu is studied for its roles in wound healing, collagen synthesis, anti-inflammatory activity, and tissue remodeling. It naturally declines with age and is a focus of regenerative medicine research.

Why does NAD+ matter for aging research?

NAD+ is essential for sirtuin and PARP enzyme activity, which regulate DNA repair and cellular stress responses. NAD+ levels decline significantly with age, making it a key target in longevity research.

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Research-grade anti-aging peptides from Apollo Peptide Sciences. Third-party tested, >98% purity guaranteed.

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